GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
---|---|---|---|---|---|---|---|---|---|---|---|
BLCA | cis | rs4803480 | 1 | rs7255679 | chr19:42063981 | CEACAM21 | chr19:42055886-42093196:+ | 0.35 | 7.77 | 7.32E-14 | Schizophrenia |
BLCA | cis | rs7246967 | 1 | rs7257127 | chr19:23056699 | ZNF492 | chr19:22817126-22850472:+ | -0.31 | -4.16 | 3.95E-5 | Bronchopulmonary dysplasia |
BLCA | cis | rs7258015 | 1 | rs7257871 | chr19:10449252 | YIPF2 | chr19:11033446-11039357:- | 0.24 | 3.9 | 0.000114 | Systemic lupus erythematosus or rheumatoid arthritis |
BLCA | cis | rs7258015 | 1 | rs7258015 | chr19:10449358 | YIPF2 | chr19:11033446-11039357:- | 0.24 | 3.9 | 0.000114 | Systemic lupus erythematosus or rheumatoid arthritis |
BLCA | cis | rs12220777 | 1 | rs72644213 | chr10:81783660 | LOC219347 | chr10:81805991-81838949:- | 0.35 | 4.14 | 4.36E-5 | Chronic obstructive pulmonary disease-related biomarkers |
BLCA | cis | rs7112513 | 1 | rs72645460 | chr11:116771375 | PCSK7 | chr11:117075789-117102811:- | 0.45 | 5.5 | 7.0E-8 | Protein quantitative trait loci |
BLCA | cis | rs4372836 | 1 | rs72782294 | chr2:28953390 | TRMT61B | chr2:29072690-29093175:- | 0.29 | 5.09 | 5.59E-7 | Body mass index |
BLCA | cis | rs7428 | 1 | rs72840063 | chr2:85550396 | TGOLN2 | chr2:85545147-85555374:- | -0.22 | -5.33 | 1.66E-7 | Ear protrusion |
BLCA | cis | rs41266839 | 1 | rs72843784 | chr6:26498758 | BTN3A2 | chr6:26365398-26378546:+ | -0.77 | -7.63 | 1.86E-13 | Schizophrenia |
BLCA | cis | rs1930961 | 1 | rs7285549 | chr22:25874580 | CRYBB2 | chr22:25615612-25627836:+ | 0.93 | 9.86 | 1.33E-20 | Bipolar disorder with mood-incongruent psychosis |
BLCA | cis | rs13053817 | 1 | rs7290684 | chr22:29857664 | NIPSNAP1 | chr22:29950800-29977144:- | 0.28 | 4.03 | 6.64E-5 | Carotid atherosclerosis in HIV infection |
BLCA | cis | rs13053817 | 1 | rs7290855 | chr22:29852474 | MTMR3 | chr22:30279158-30426855:+ | 0.25 | 3.95 | 9.17E-5 | Carotid atherosclerosis in HIV infection |
BLCA | cis | rs13053817 | 1 | rs7290855 | chr22:29852474 | NIPSNAP1 | chr22:29950800-29977144:- | 0.27 | 3.85 | 0.000137 | Carotid atherosclerosis in HIV infection |
BLCA | cis | rs732528 | 1 | rs72929710 | chr18:48372427 | MRO | chr18:48321491-48351754:- | 0.25 | 4.42 | 1.29E-5 | Entorhinal cortical thickness |
BLCA | cis | rs732528 | 1 | rs72929734 | chr18:48381990 | MRO | chr18:48321491-48351754:- | 0.25 | 4.39 | 1.5E-5 | Entorhinal cortical thickness |